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・ Methylindole
・ Methylisocitrate lyase
・ Methylisopropyllysergamide
・ Methylisopropyltryptamine
・ Methylisothiazolinone
・ Methylisothiazolone
・ Methylitaconate Delta-isomerase
・ Methylketobemidone
・ Methylliberine
・ Methyllinderone
・ Methyllithium
・ Methyllycaconitine
・ Methyllysine
・ Methylmagnesium chloride
・ Methylmalonate semialdehyde dehydrogenase
Methylmalonate-semialdehyde dehydrogenase (acylating)
・ Methylmalonic acid
・ Methylmalonic acidemia
・ Methylmalonyl CoA epimerase
・ Methylmalonyl-CoA
・ Methylmalonyl-CoA carboxytransferase
・ Methylmalonyl-CoA decarboxylase
・ Methylmalonyl-CoA mutase
・ Methylmalonyl-CoA mutase deficiency
・ Methylmercuric dicyanamide
・ Methylmercury
・ Methylmescaline
・ Methylmethaqualone
・ Methylmethcathinone
・ Methylnaltrexone


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Methylmalonate-semialdehyde dehydrogenase (acylating) : ウィキペディア英語版
Methylmalonate-semialdehyde dehydrogenase (acylating)

In enzymology, a methylmalonate-semialdehyde dehydrogenase (acylating) () is an enzyme that catalyzes the chemical reaction
:2-methyl-3-oxopropanoate + CoA + H2O + NAD+ \rightleftharpoons propanoyl-CoA + HCO3- + NADH
The 4 substrates of this enzyme are 2-methyl-3-oxopropanoate, CoA, H2O, and NAD+, whereas its 3 products are propanoyl-CoA, HCO3-, and NADH.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating). Other names in common use include MSDH, and MMSA dehydrogenase. This enzyme participates in 3 metabolic pathways: inositol metabolism, valine, leucine and isoleucine degradation, and propanoate metabolism.
==Structural studies==

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .

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